Medications for POTS

There is currently no cure for postural orthostatic tachycardia syndrome (POTS). These medications are prescribed off-label; meaning that they were designed for other disorders but have not been approved for POTS by the U.S. Food and Drug Administration.  They may, however, help alleviate POTS symptoms and often require trial and error to find the best combination for individual patients. Here are some of the more common medications used to treat POTS symptoms.

Frontiers Update of Individualized Treatment Strategies for Postural Orthostatic Tachycardia Syndrome in Children

Robert Lustig MD - Some COVID long-haulers are being diagnosed with a little-known condition called POTS. Check out this handy treatment guide from

Postural orthostatic tachycardia syndrome - Wikipedia

POTS Syndrome, an Invisible Disease

Medication for POTS + Other Treatments That Work

Postural Tachycardia Syndrome (POTS) Diagnosis and Treatment: Basics and New Developments - American College of Cardiology

Management of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia and Vasovagal Syncope

Postural Orthostatic Tachycardia Syndrome - Practical Neurology

Pharmacological and Non-Pharmacological Interventions for Postural Orthostatic Tachycardia Syndrome (POTS): A Systematic Review of the Literature