Drug-Like Molecules Regenerate Hair Cell-Like Cells in Adult Mice

“Think about a brake when driving a car,” Chen explains. “If the brake is always engaged, you can’t drive. We found an siRNA that could remove the brake in this genetic pathway.”

Hearing Health Foundation (HHF) is the largest non-profit funder of hearing research. Since 1958, HHF has given away millions of dollars to hearing and balance research, including work that led to cochlear implant technology and now through the Hearing Restoration Project is working on a cure for hearing loss and tinnitus. HHF also publishes Hearing Health magazine, a free consumer resource on hearing loss and related technology, research, and products.

Frontiers Regenerated hair cells in the neonatal cochlea are innervated and the majority co-express markers of both inner and outer hair cells

IJMS, Free Full-Text

AAV-ie-K558R mediated cochlear gene therapy and hair cell regeneration

Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear

TRIM71 reactivation enhances the mitotic and hair cell–forming potential of cochlear supporting cells

Application of insulin-like growth factor-1 in the treatment of inner ear disorders

Day 8 reprogrammed hair cells are inner hair cell-like, innervated

Normal Development and Formation of Hair Cells in Both Wild-Type and

Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear

Brain Connectivity Patterns in Children With Autism Spectrum

IJMS, Free Full-Text

Identification of mouse cochlear progenitors that develop hair and supporting cells in the organ of Corti