Single-cell analysis of Crohn's disease reveals a detailed picture of inflammation in the gut

Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn
Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn's disease, a chronic condition in which a hyperactive immune system causes inflammation throughout the gut, leading to symptoms including abdominal pain, diarrhea, and weight loss. The disease is difficult to treat and often requires hospitalization.

10 New Genetic Variants of Crohn's Disease Susceptibility Uncovered

Science in Boston

inflammatory bowel disease – NIH Director's Blog

Persistence of Lgr5+ colonic epithelial stem cells in mouse models of inflammatory bowel disease

Workshops Broad Institute

Human Cell Gut Atlas project maps all the cell types in the intestines., Propel a Cure for Crohn's Disease posted on the topic

Single-cell analyses of Crohn's disease tissues reveal intestinal

Xavier lab Broad Institute

Ramnik Xavier named as a core member of Broad Institute